Optimmune® Ophthalmic Ointment for Dogs: Eye Care
Did you know that Optimmune® Ophthalmic Ointment for Dogs has gotten 67 reviews? An amazing 91% of people would tell a friend about it1. This vet-approved medicine, with 0.2% Cyclosporine, USP, is a big deal for treating chronic dry eye and chronic superficial keratitis in dogs2.
Key Takeaways
- Optimmune® Ophthalmic Ointment is the only FDA-approved veterinary cyclosporine product for dogs, providing a specialized treatment option for chronic KCS and CSK.
- The preservative-free formulation helps reduce the chance of secondary infection and chemical irritation.
- Optimmune® can be stored for up to 24 months without refrigeration, ensuring stability and longevity of the product.
- Customers report high satisfaction with Optimmune®, with an overall rating of 4.82 out of 5 stars based on 67 reviews.
- Optimmune® is primarily prescribed to treat KCS and CSK in dogs, with a 3.5g tube lasting approximately 6 weeks when used as instructed.
Table of Contents
Optimmune® (0.2% Cyclosporine, USP) Ophthalmic Ointment for Dogs
Understanding the Formulation and Uses
Optimmune® Ophthalmic Ointment is a special medicine for dogs. It has 0.2% cyclosporine, USP3. This medicine helps reduce swelling and boost tear production in dogs with chronic eye problems like KCS and CSK3. It doesn’t have any preservatives to lower the chance of infection or irritation3.
FDA Approval and Unique Features
Optimmune® is the only eye medicine for dogs that is FDA-approved3. It stands out because it’s free from preservatives and lasts up to 24 months without needing to be kept cold3.
Optimmune® is special because it works as a local immune modulator. It treats eye problems without causing harm throughout the body. Plus, it keeps well for up to 24 months without needing to be kept cold3.
Product Details | Optimmune® (0.2% Cyclosporine, USP) Ophthalmic Ointment |
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Merck SKU | 0588044 |
Price | $65.994 |
Size | 3.5 gm4 |
Usage Frequency | Administer a ¼ inch strip every 12 hours to the affected eye(s)4 |
Active Ingredient | Cyclosporine 2 Mg, USP4 |
Veterinary Recommendation | Recommended to be used under professional supervision4 |
Side Effects | Possible irritation or redness of the eye4 |
Prescription Item | Non-returnable and non-refundable4 |
Purpose | Manages chronic dry eye keratoconjunctivitis sicca and pannus chronic superficial keratitis in dogs4 |
Storage Instructions | Store in a cool, dry place away from direct light, keep out of reach of children and pets4. |
“Optimmune® is the only FDA-approved veterinary cyclosporine ophthalmic product available on the market.”3
Treating Chronic Keratoconjunctivitis Sicca (KCS) and Chronic Superficial Keratitis (CSK)
Optimmune® Ophthalmic Ointment is used to treat chronic keratoconjunctivitis sicca (KCS or dry eye) and chronic superficial keratitis (CSK) in dogs5. These conditions cause eye dryness, irritation, and discomfort in dogs5.
For dogs with chronic KCS, apply a 1/4 inch strip of Optimmune® Ophthalmic Ointment to the eye every 12 hours5. Starting treatment early helps prevent serious damage5. Dogs with KCS or CSK need ongoing treatment for life56.
In a KCS trial, 20 out of 132 dogs had side effects, 12.9% on Optimmune and 22.6% on placebo5. In the CSK trial, 5.6% of dogs had side effects like eye redness and mild discomfort56.
Optimmune® Ophthalmic Ointment has 0.2% Cyclosporine for chronic KCS and CSK in dogs6. Safety tests showed no harm in adult dogs even at high doses5.
UV radiation can affect how well CSK treatment works6. If cyclosporine doesn’t work, a different treatment plan may be needed6.
It can be hard to tell if a dog is reacting badly to treatment if they already have a lot of inflammation5. Keep Optimmune Ophthalmic Ointment between 2° and 25°C (36° and 77°F)57.
In conclusion, Optimmune® Ophthalmic Ointment is a key tool for vets treating KCS and CSK in dogs. It’s effective, safe, and easy to use. Optimmune® can help reduce eye discomfort and prevent vision problems in dogs.
Benefits of Cyclosporine Ophthalmic Ointment for Canine Eye Conditions
Optimmune® (0.2% Cyclosporine, USP) Ophthalmic Ointment is a key tool for treating chronic eye issues in dogs. It uses cyclosporine to boost tear production and lessen inflammation8. This makes it a top pick for managing conditions like Keratoconjunctivitis Sicca (KCS) and Chronic Superficial Keratitis (CSK).
Stimulating Tear Production and Reducing Inflammation
Cyclosporine in Optimmune® fights inflammation and protects the tear glands8. It also encourages the body to make more tears, solving the main issue of dry eye in dogs8. This approach is key to easing KCS and CSK symptoms, which include not enough tears and swelling.
Preservative-Free Formulation for Safe Long-Term Use
Optimmune® doesn’t have preservatives, which is great for vets and pet owners dealing with chronic eye issues in dogs9. Without preservatives, there’s less chance of infections or irritation, making it safe for long-term use9. This is especially good for dogs needing ongoing care, as it lowers the risk of problems and keeps the pet comfortable during treatment.
“Cyclosporine-based ointments like Optimmune® are an essential tool for veterinary professionals in the management of chronic canine eye conditions.”
Optimmune® Ophthalmic Ointment helps by making more tears, reducing swelling, and being preservative-free. This makes it a full solution for long-term care of KCS and CSK in dogs8910. It’s a must-have for vets and pet owners, helping dogs with these ongoing eye problems stay comfortable and healthy8910.
Administering Optimmune® Ophthalmic Ointment
Dosage and Application Guidelines
Optimmune® Ophthalmic Ointment is only approved for dogs by the FDA11. It should be applied as a ¼ inch strip to the affected eye(s) every 12 hours11. It’s important to apply it correctly to avoid contamination and get the best results.
You can put the ointment on the cornea or in the conjunctival sac11. Cyclosporine, the main ingredient, helps reduce eye inflammation11. While serious side effects are rare, you might see minor ones like burning, redness, or blurred vision11.
Missed Dose Instructions
If you miss a dose, apply it as soon as you remember11. Keep up with the twice-daily schedule to keep the medication working well. Not using it regularly can make the eye condition worse11.
Using Optimmune® Ophthalmic Ointment regularly is key for treating eye problems in dogs11. Missing doses or applying it unevenly can reduce its effectiveness and harm your pet’s eyes.
“Proper administration of Optimmune® Ophthalmic Ointment is essential for achieving the best possible outcomes for dogs suffering from chronic eye conditions.”
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Potential Side Effects and Precautions
Pet owners should know about the possible side effects of Optimmune® Ophthalmic Ointment for dogs. This medication is usually safe, but some dogs might have mild reactions like eye or eyelid inflammation, redness, and discomfort13. These reactions are often short-lived and might be because the condition wasn’t fully controlled, not a reaction to the medicine13.
In tests, 12.9% of dogs using Optimmune® Ophthalmic Ointment had side effects, compared to 22.6% on a placebo13. In a study on chronic superficial keratitis, only 5.6% of 36 cases had adverse reactions13. No toxicity or side effects were seen in dogs given up to 10 times the usual dose in a safety study13.
Dogs with eye infections before using Optimmune® Ophthalmic Ointment should be watched closely13. If side effects last more than 7 days, see a vet13. Dogs with conditions like KCS or CSK might need to use this medicine forever to get the best results13.
The main ingredient in Optimmune® Ophthalmic Ointment, cyclosporine, is safe14. It has a low toxicity level and is safe in rats, with an LD50 of 1480 mg/kg14. Long-term studies in rats showed serious kidney and liver problems only at very high doses14. Cyclosporine also didn’t show any signs of causing cancer or genetic mutations in animal tests14.
Overall, Optimmune® Ophthalmic Ointment is a safe choice for treating eye problems in dogs, with only a few mild side effects15. Use it carefully in dogs with eye infections, and talk to a vet if side effects don’t go away13. With careful use and monitoring, it can be a safe and effective way to help dogs with chronic eye issues15.
Comparison with Other Cyclosporine Eye Treatments
Optimmune® is the only FDA-approved cyclosporine eye treatment for dogs16. It has a special formula without preservatives and lasts longer than other treatments7. This might make it safer and easier to use. The cost can also affect what vets and pet owners choose.
Efficacy, Cost, and Convenience Factors
Cyclosporine is the first and only drug in its class16. Optimmune® was approved in 1995 for canine dry eye in the US and for dry eye and pannus in Europe16. About 80% of dogs with dry eye get better with cyclosporine treatment16. Most dogs need to keep taking it to keep their eyes from getting dry again16.
Optimmune® might be cheaper and easier to use than other cyclosporine treatments7. It doesn’t have preservatives and lasts longer, making it a good choice for pet owners7. You just need to put a small amount in the eye twice a day, which is simple7.
Using Optimmune® might cause some eye irritation, but it’s generally safe7. This is good news for pet owners looking for a long-term solution for their dog’s eye problems.
“Cyclosporine is unlikely to penetrate well into the inner eye and is seldom used to treat anterior uveitis due to its high concentrations in the cornea, conjunctiva, sclera, and lids where it is useful for suppressing chronic immune-mediated diseases.”16
In summary, Optimmune® is a top choice for cyclosporine eye treatments for dogs167. It’s FDA-approved, has no preservatives, and is easy to use. These benefits make it a great option for vets and pet owners dealing with dry eye and other eye issues in dogs.
Veterinary Ophthalmology: Optimmune® Ophthalmic Ointment’s Role
Optimmune® Ophthalmic Ointment is key in treating chronic eye problems in dogs like KCS and CSK. It’s made just for vets and is approved by the FDA. This makes it a top choice for treating immune-related eye issues in dogs3.
KCS is a common eye problem in dogs. It causes the cornea and conjunctiva to get inflamed and dry. This happens often because the tear glands don’t work right17. Some dog breeds like the American Cocker Spaniel and Miniature Schnauzer get KCS more easily because they react to their own immune system17.
Optimmune® 0.2% Ophthalmic Ointment has changed how we treat KCS. It works well even for dogs with very dry eyes17. If regular treatments don’t work, vets can make stronger versions of this medicine for each dog17.
Optimmune® is safe and effective for treating KCS and CSK in dogs. It doesn’t harm the body overall. Its special formula means it’s safe for long-term use3.
Feature | Description |
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Shelf Life | Up to 24 months with no refrigeration required3 |
Reported Side Effects | Ocular and periocular inflammatory reactions, transient hyperemia, epiphora, mild discomfort of the eye, and mild alopecia in a small number of treated dogs3 |
FDA Approval | Optimmune® is the only FDA-approved veterinary cyclosporine ophthalmic product3 |
Manufacturer Cautions | Safety not determined in cases of preexisting viral or fungal ocular infections, nor in puppies, pregnant bitches, or dogs used for breeding3 |
Optimmune® Ophthalmic Ointment is a big help in veterinary eye care. It lasts a long time, has few side effects, and is the only FDA-approved cyclosporine ointment for dogs3. It’s a key tool for vets who want the best for their dog patients.
Conclusion: A Comprehensive Solution for Canine Dry Eye Management
Optimmune® Ophthalmic Ointment is a top choice for managing chronic eye problems in dogs. It has an FDA-approved formula and doesn’t have preservatives. This makes it safe for dogs with chronic keratoconjunctivitis sicca (KCS) and chronic superficial keratitis (CSK)18.
The main ingredient, cyclosporine, helps make more tears and reduces swelling. These are key to fighting dry eye in dogs19. Plus, it doesn’t have preservatives, so it’s safe for dogs to use for a long time.
Studies on Optimmune® show it works well. Dogs with KCS got better tear production, thanks to it20. This proves Optimmune® is a great solution for vets and dog owners dealing with dry eye in dogs.
FAQ
What is Optimmune® Ophthalmic Ointment?
What are the key features of Optimmune® Ophthalmic Ointment?
How does Optimmune® work to treat canine eye conditions?
How is Optimmune® Ophthalmic Ointment administered?
What are the potential side effects of Optimmune® Ophthalmic Ointment?
How does Optimmune® compare to other cyclosporine eye treatments for dogs?
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Source Links
- Optimmune (cyclosporine) Ophthalmic Ointment
- Optimmune Ophthalmic Ointment | Mountainview Small Animal Hospital
- Optimmune® 0.2% Ophthalmic Ointment
- Eye Relief with Optimmune Dogs 0.2% Ointment | HardyPaw
- Optimmune Ophthalmic Ointment for Dogs – (0.2% Cyclosporine,USP) – 3.5 gm (3-Pack) – [Dry Eye]
- Optimmune Ophthalmic Ointment | FC
- Optimmune (0.2% Cyclosporine) Ophthalmic Ointment
- Optimmune® (0.2% Cyclosporine, USP) Ophthalmic Ointment
- Optimmune Ophthalmic Ointment for Dogs – (0.2% Cyclosporine,USP) – 3.5 gm – [Dry Eye]
- Optimmune Ophthalmic Ointment | Hillcrest Veterinary Hospital
- Optimmune Ophthalmic Ointment 0.2% 3.5 gm Tube | 1800PetMeds
- FOI Summary for Supplemental Approval of NADA 141-052 August 26, 1997
- Optimmune Ophthalmic Ointment
- MATERIAL SAFETY DATA SHEET
- Optimmune Ophthalmic Ointment 0.2%
- Cyclosporine for Veterinary Use
- Dry Eye – Mar Vista Animal Medical Center
- Ophthalmic delivery of cyclosporine A by punctal plugs
- Cyclosporine ophthalmic emulsions for the treatment of dry eye: a review of the clinical evidence
- US20130345185A1 – Ophthalmic Compositions – Google Patents