Metoclopramide Dog Dosage Calculator
Accurate metoclopramide dosing for dogs by weight and route — covering intermittent oral dosing and continuous rate infusion (CRI) for gastric motility disorders and emesis control.
Extrapyramidal effects possible. Metoclopramide crosses the blood-brain barrier. Do not use in dogs with epilepsy, GI obstruction, or pheochromocytoma. Veterinary supervision required.
What Is Metoclopramide?
Metoclopramide is a dopamine D2-receptor antagonist and prokinetic agent that enhances gastric emptying and coordinates antroduodenal motility. It also exerts central antiemetic effects by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ). In dogs it is used for delayed gastric emptying, gastroesophageal reflux, megaesophagus, and post-operative nausea.
CRI (continuous rate infusion) maintains steadier plasma levels than intermittent dosing and is preferred in hospitalized patients with severe ileus or intractable vomiting. Available as 5 mg and 10 mg tablets, 5 mg/5 mL syrup, and 5 mg/mL injectable solution.
Key Pharmacology
- Mechanism: D2 antagonist (CTZ + gut); also weak 5-HT4 agonist (prokinesis)
- Oral bioavailability: 60–80% in dogs
- Half-life: ~1.5 hours; CNS effects outlast plasma levels
- Contraindications: GI obstruction/perforation, epilepsy, pheochromocytoma, concurrent opioids (may enhance CNS effects)
How to Use This Calculator
- Enter your dog’s body weight in kg or lbs
- Choose the administration route (oral or CRI)
- Select the available formulation strength
- Click Calculate to see dose per administration and frequency
🧮 Metoclopramide Dose Calculator
Metoclopramide Dosing Result
References
- Plumb DC. Plumb’s Veterinary Drug Handbook, 9th ed. Wiley-Blackwell; 2018.
- Washabau RJ, Elie MS. Antiemetic therapy. In: Kirk’s Current Veterinary Therapy XIII. WB Saunders; 2000.
- Marks SL, et al. ACVIM consensus statement on gastroprotectant use. J Vet Intern Med. 2018;32(6):1823-1840.