Fenbendazole (Panacur®, Safe-guard®) for Horses: Usage

Panacur® includes fenbendazole, an important part of horse deworming. It’s FDA-approved and targets various worms. These include big and small strongyles, pinworms, and roundworms¹.

Using this anthelmintic is key for horse health across the U.S¹. It joins deworming schedules to keep horses healthy and happy.

Key Takeaways

• Panacur® (fenbendazole) is FDA-approved for use in horses, cattle, swine, and goats to treat various parasitic worms.
• Safe-guard® is an over-the-counter dewormer containing the same active ingredient and concentration as Panacur®.
• Regular deworming intervals of 6-8 weeks may be necessary for horses due to the risk of reinfection.
• Fenbendazole medications are generally well-tolerated in horses, but higher doses may lead to allergic reactions.
• Proper storage and handling guidelines must be followed to ensure the safety and efficacy of fenbendazole products.

What is Fenbendazole for Horses?

Fenbendazole is a trusted dewormer for horses. It’s sold as Panacur® and Safe-guard®². The FDA approves it for treating and controlling different worms in horses².

Definition and Brand Names

Panacur® and Safe-guard® are top names for fenbendazole. Panacur® is the official version. Safe-guard® is an easy-to-get version with the same stuff inside³. Sometimes, vets might give a different version if needed for a certain horse.

FDA-Approved and Over-the-Counter Formulations

Panacur® Equine Dewormer Paste is the FDA top pick. It has 100 mg of fenbendazole in every gram³. For horses, the right dose is 2.3 mg per pound. This helps fight off certain worms. Safe-guard® also has this same helpful ingredient.

Fenbendazole works well for keeping horses healthy. It fights off many worm types. Knowing about this dewormer is key for horse owners and vets²³.

Understanding Fenbendazole’s Mode of Action

Fenbendazole is a powerful deworming drug. It works in a unique way to kill parasitic worms. By stopping the worms from making energy, it makes them starve and die⁴.

This drug stops a protein called tubulin from working right. Tubulin helps worms with their structure and movement. So, these parasites can’t take in nutrients or move well. This leads to their death⁵.

But here’s the cool part: fenbendazole doesn’t just get rid of adult worms. It also takes out the young ones, like larvae and eggs, stopping them from growing. This means it helps lower the number of parasites in the host⁴.

This drug’s action is so wide-ranging, it’s good for fighting many worm types in horses and other animals. This broad action is key to keeping horses and livestock healthy⁶.

In short, fenbendazole works by messing up parasites’ energy-making and structure, leading them to die. It hits both adult and young worms, making it a strong weapon against these pests. This makes it a top pick for maintaining animals’ health⁴⁵⁶.

Benefits of Fenbendazole for Equine Deworming

Fenbendazole products like Panacur® and Safe-guard® are top choices for getting rid of strongyles, pinworms, and roundworms in horses⁷. They’re safe for horses at any age, even pregnant mares and young foals⁸. This medicine fights different parasites in horses, like roundworms, hookworms, and certain tapeworms⁷.

Fenbendazole is great at fighting a wide range of internal parasites in horses⁷. You give it to the horse once a day for three days then do it again 2-3 weeks later⁷. It starts working within a day or two, and you soon see the effects during the treatment⁷.

This dewormer is safe and works well, with only a few possible side effects like too much drooling, throwing up, or loose poop⁷. Most horses handle it well⁷. It’s also safe for pregnant mares and young foals. This makes it important for keeping a wide range of horse groups free from parasites⁸.

Vets might check your horse’s poop after deworming to be sure all the parasites are gone⁷. Keeping fenbendazole in the right place and using it correctly keeps it working as it should⁷.

“Fenbendazole is a highly effective dewormer that can help protect horses from a variety of internal parasites, making it a valuable tool for equine health and well-being.”

In conclusion, fenbendazole is a key tool in managing internal parasites in horses⁸. It’s favored for its safety and strong effect against various parasites⁹. This makes it a top choice for keeping horses healthy, no matter their age or life stage⁷.

Administering Fenbendazole to Horses

Getting fenbendazole right is key for treating worms in horses. It’s known by the names Panacur® and Safe-guard® and is a FDA-approved medicine for horses, cows, pigs, and goats¹.

Dosage and Frequency

Horses should get 2.3 mg for every pound they weigh to fight worms. This dose is for big and small strongyles, and pinworms¹. For younger horses where roundworms are common, it’s raised to 4.6 mg per pound¹. If there’s a risk from certain types of worm larvae, they need the higher dose for five days in a row¹.

Because horses can get worms again, they might need to be treated every six to eight weeks¹. Keeping to this routine helps stop worms from getting too strong against the treatments.

Directions for Use

Give the fenbendazole by mouth with a syringe. Place it at the back of the horse’s tongue¹. This makes sure they swallow it all, cutting down on wasted medicine.

It’s worth knowing that besides Panacur® and Safe-guard®, your vet may give you another brand. They could mix a different medicine for the horse’s special needs¹.

With the right vet guidance, you can manage deworming well. This includes using fenbendazole in a smart way for your horses¹¹.

Fenbendazole (Panacur®, Safe-guard®) for Horses

Panacur® and Safe-guard® are medicines for getting rid of worms in horses. These medicines are known as fenbendazole. They are great for treating different kinds of worms in not just horses but also cows, pigs, and goats¹.

This medicine works by stopping the worms from making energy. This makes the worms starve and die. Owners can buy these medicines without a prescription to help keep their horses healthy¹.

• Safe-Guard Animal Health Equine Dewormer Paste contains 10% fenbendazole for effective treatment of horses¹².
• Each gram of Safe-Guard Paste contains 100 mg of fenbendazole¹².
• Safe-Guard Paste helps control many worms in horses¹².

Horses should be dewormed every six to eight weeks. This helps stop worms from coming back. Panacur® and Safe-guard® are usually safe for horses and don’t cause a lot of side effects¹.

But, some horses might have allergies to this medicine. If used right, it’s good in keeping the parasites, like some worms, under control¹². Fenbendazole, found in products like Panacur® and Safe-guard®, is very important for keeping horses safe from harmful parasites1¹

Potential Side Effects and Precautions

The equine dewormers Panacur® and Safe-guard® are safe for horses when used properly¹³. They usually don’t cause big problems. But, horse owners need to know a few things.

Allergic Reactions and Hypersensitivity

At times, giving too much fenbendazole can lead to bad stuff from dead parasites. This might cause allergic reactions or hypersensitivity. Watch out for signs like an itchy skin, hard breathing, and stomach troubles such as throwing up or runny poop¹³. Severe effects, like bone marrow issues, welts, a puffy face, and breathing issues, suggest an allergic response. In this case, your horse needs to see the vet right away¹³.

Pregnant and Lactating Mares

It’s safe to use fenbendazole on pregnant and nursing mares if you follow the right steps. Still, talking to your vet before giving it is smart. This ensures safety and the right instructions are understood.

“Consultation with your veterinarian is recommended when using any dewormer, especially in sensitive populations like pregnant or nursing mares.”

Knowing about side effects and how to prevent them helps keep your horse healthy. Use Panacur® and Safe-guard® safely to care for your horse¹⁴.

Comparing Fenbendazole to Other Dewormers

Fenbendazole in products like Panacur® and Safe-guard® works well as deworming medicine for horses. Yet, some small strongyles are not affected by it anymore¹⁵. To avoid this problem, vets suggest using fenbendazole with other dewormers. They also advise rotating it with different types of dewormers¹⁶.

Efficacy and Resistance Management

Research has found that nearly all farms, 97.7%, faced fenbendazole resistance. However, ivermectin was still effective without any resistance in these tests¹⁵. Notably, over half of the farms, 53.5%, showed oxibendazole resistance, and 40.5% had resistance to pyrantel pamoate¹⁵. When these dewormers were used, fecal egg counts dropped by 24.8% for fenbendazole, 99.9% for ivermectin, 73.8% for oxibendazole, and 78.6% for pyrantel pamoate¹⁵.

In the southern United States, resistance to fenbendazole, oxibendazole, and pyrantel pamoate was more common than before¹⁵. Similarly, the UK, Australia, and Brazil are seeing resistance to a class of drugs called avermectin/milbemycin (AM)¹⁵. This shows we have a global issue. Even ivermectin, which has worked well previously in the US, is starting to have less effect¹⁵.

Picking the right dewormer is crucial for your horse’s health. By using different dewormers and other parasite control methods, you can prevent resistance. This makes sure dewormers keep working well¹⁶⁹.

¹⁵¹⁶⁹

Storage and Handling Guidelines

It’s vital to store and handle horse deworming meds like Fenbendazole (Panacur®, Safe-guard®) right. This keeps them effective and safe for animals and humans¹.

The product info says Panacur® and Safe-guard® must be kept at or below 25°C (77°F) to avoid freezing¹. For compounded fenbendazole, follow the compound pharmacy’s storage suggestions¹. Make sure to keep these medicines away from kids and pets to avoid swallowing them by mistake¹.

When using fenbendazole, be careful and stick to the safety tips. Wear gloves and don’t touch the meds with bare skin. This helps lower the chance of allergies caused by dead parasites releasing harmful substances¹.

While overdosing on fenbendazole isn’t toxic to horses, it can cause an allergic reaction¹. So, it’s key to give the right amount following the label or vet’s advice².

Adhering to these guidelines, horse owners can confidently use Fenbendazole (Panacur®, Safe-guard®) for their horses¹¹⁴².

Missed Dose Instructions

Missing a dose of fenbendazole, an important horse dewormer, is a worry¹⁷. If you miss a dose, talk to your vet for advice¹⁷.

Your vet might say to give the missing dose right away. Or they might say to just skip it and continue the regular schedule¹⁷. They consider the horse’s deworming plan, health, and when the dose was missed.

1. If you miss a dose and realize it soon, the vet might tell you to give it to keep up with the plan.
2. But, if it’s already late in the schedule, they could advise not giving the missed dose. This helps prevent giving too much and any problems that might come with it.

It’s vital to carefully follow what your vet says about missed doses of fenbendazole¹⁷. Doing something different might make the dewormer less effective. This, in turn, could make the parasites in your horse resistant to the medicine¹⁸.

Always stay in touch with your vet about deworming, especially if you miss a dose¹⁷. They will guide you on what to do. Their advice is critical to your horse’s health and safety¹⁷.

By sticking to the deworming plan, you’re looking out for your horse’s health¹⁷. Regular deworming is important for keeping parasites under control. This helps prevent any health issues that might come up¹⁸.

Signs of Overdose and Toxicity

Overdosing on fenbendazole, found in Panacur® and Safe-guard®, usually won’t badly harm horses. But, it can still cause bad reactions¹⁹. An overdose might make horses react badly or be more sensitive because of toxins from dying parasites²⁰.

If a horse has too much fenbendazole, its owner must act fast. They should call the vet or go to an emergency vet¹⁹. Signs of an overdose in horses are:

• Vomiting
• Diarrhea
• Loss of appetite
• Excessive drooling
• Allergic reactions, such as hives or swelling

In few cases, overdose from dewormers like Panacur® can be worse. It might cause issues like harming the bone marrow or pancytopenia²⁰. Owners need to watch their horses for odd symptoms. They should contact the vet quickly if they worry about an overdose.

Using fenbendazole properly is very important for safety. Follow the vet’s and label’s dosage carefully¹⁹. Always give the right dose for your horse’s size and type of worm to stop an overdose and bad side effects¹⁹.

If you think your horse overdosed on fenbendazole, act quickly. Call the vet or a poison control center for animals. They’ll tell you what to do next¹⁹. Fast vet help lowers the chance of severe issues and keeps your horse safe.

Conclusion

Panacur® and Safe-guard® are great choices for deworming horses¹⁶. They’re effective and safe when used right. But, it’s key to plan with a vet for deworming. It’s vital to mix up treatments to avoid parasite resistance¹⁶. This is crucial because many parasites are getting more resistant to dewormers. If we don’t change our approach, all parasites might resist against dewormers in ten years²¹.

To tackle this issue, using fecal egg counts to pinpoint which horses need deworming can help. This method also helps keep some parasites in a ‘refuge’ to slow resistance²². By keeping up with the latest in deworming advice and working closely with vets, horse owners can protect their horses’ health better. They can also effectively fight dewormer resistance²¹²².

In brief, using fenbendazole products wisely is crucial for keeping them effective over time¹⁶²¹²². This underscores the need for smart, proactive deworming to beat equine parasites over the long haul¹⁶²¹²².

Source Links

1. Fenbendazole (Panacur®, Safe-guard®) for Horses
2. panacur® (fenbendazole) Horse & Cattle Dewormer
3. Panacur Equine Dewormer Paste (Fenbendazole), 25 gm
4. Fenbendazole for Pancreatic Cancer: What Research Shows
5. Fenbendazole as a Potential Anticancer Drug
6. Fenbendazole for Cats: Overview, Dosage & Side Effects – Cats.com
7. Fenbendazole | VCA Animal Hospitals
8. SAFE-GUARD® (fenbendazole) | Merck Animal Health USA
9. Decoding Dewormers: Types, Resistance Concerns, and Use for Horses
10. No title found
11. PDF
12. Safe-Guard Animal Health Equine Dewormer Paste, 25 gm
13. PDF
14. Fenbendazole | VCA Animal Hospitals
15. Microsoft Word – FL Equine Institute 2009 proceedings
16. Which is the Best Horse Dewormer?
17. PDF
18. Updating How We Deworm Horses – Avon Animal Hospital
19. Panacur For Dogs: Safe Dosages And Uses
20. Dear Vet Letter regarding AERs associated with ELU of fenbendazole
21. Parasite Control | McGee Equine Veterinary Clinic
22. New Deworming Recommendations: Resistance on the Rise | Equine Medical Service