Solensia™ (frunevetmab injection) for cats

Solensia™: Ease Cat Osteoarthritis Pain Now

Picture your cat leaping, exploring, and snuggling with new joy and ease. This dream is now real, thanks to Solensia™. It’s the first FDA-approved drug that uses a special protein to fight osteoarthritis (OA) pain in cats1. After only one shot of Solensia™, 77% of cat owners noticed big improvements in their pets’ pain2. This new medicine is changing life for cats and their people, giving them hope against OA’s tough effects.

Osteoarthritis is common in cats, especially those over 12, affecting up to 90% of them1. Many cat owners don’t know pain is the main sign of the disease. This lack of awareness can hurt a cat’s overall happiness. Solensia™ uses a special way to fight OA pain by blocking NGF, a factor in pain1. This means it can bring long-lasting comfort to our furry friends.

Key Takeaways

  • Solensia™ is the first FDA-approved injectable monoclonal antibody therapy for controlling osteoarthritis pain in cats.
  • In clinical studies, 77% of cat owners reported improved signs of pain in their pets after a single monthly Solensia™ treatment2.
  • Solensia™ specifically targets nerve growth factor (NGF), a key driver of osteoarthritis pain in cats, providing a novel approach to pain management.
  • Cats treated with Solensia™ demonstrated increased mobility, activity levels, and overall well-being2.
  • Solensia™ is well-tolerated, with the most common side effects being vomiting and injection site pain2.

What is Solensia™ (frunevetmab injection) for cats?

Solensia™ is a new kind of drug made to help cats with osteoarthritis. It’s different because it targets Nerve Growth Factor (NGF). This is a key player in sending joint pain signals3.

Frunevetmab, the key part of Solensia™, attaches strongly to NGF. By doing this, it stops pain messages from reaching the brain. So, cats feel less pain and more at ease despite their condition3.

  • Solensia™ contains 7 mg/mL of the active ingredient, Frunevetmab3.
  • The dosing chart for Solensia™ shows that cats between 2.5-7 kg should get 1 mL, while those 7.1-14 kg should have 2 mL3.

A study with 275 cats proved Solensia’s worth in managing osteoarthritis pain. In this trial, 182 got Solensia™ and 93, a control3.

Although Solensia™ is usually well-accepted, some cats had side effects. These included vomiting, pain at the injection spot, and diarrhea. A few developed antibodies to the drug, which might affect its future use3.

Solensia™ is a big step forward in helping cats with osteoarthritis. By aiming straight at what causes pain, it brings new hope. It promises to make these cats’ lives better by offering real relief4.

How Does Solensia™ Work for Feline Osteoarthritis Pain?

Understanding Solensia’s Mechanism of Action

Solensia™ is a special kind of medicine for feline osteoarthritis pain5. It’s a monoclonal antibody that works much like the body’s own antibodies, but it targets a specific pain molecule called Nerve Growth Factor (NGF)5. This action helps decrease the inflammation and counteract the pain in cats. Thus, their movement and life quality gets better.

Benefits of Solensia for Cats with Osteoarthritis

Osteoarthritis is a long-lasting condition that makes a cat’s life hard5. Solensia™ helps by making cats move better and feel more comfortable in just a few weeks5. Vets give this medicine through a shot under the skin, usually once a month. Its effects can be felt for up to four weeks after each shot1.

Solensia’s strength lies in how it targets and deals with pain. It stops NGF from working, reducing inflammation and pain5. This method is different from regular pain medicines. And this difference means it’s a more complete and effective way to manage osteoarthritis in cats.

Solensia mechanism of action

“Solensia represents a significant advancement in veterinary innovation, providing a novel and targeted approach to managing the debilitating effects of osteoarthritis in cats.”

Solensia’s way of working, along with its safety and success record, makes it a key tool for fighting feline osteoarthritis5. As a once-a-month shot, Solensia is easy for pet owners to use. It’s an effective way to reduce their cats’ pain and boost their life quality657.

Efficacy: Solensia’s Proven Results for Feline Osteoarthritis Pain Relief

Solensia™ has shown great results in easing feline osteoarthritis pain. In a key test, it helped three out of four cats control their pain over three months. This info was from their owners who used a specific tool to measure the cats’ outcomes2. Also, a smaller study found that cats on Solensia were 12.9% more active than those taking a fake pill. This increase in activity was clear within the first three weeks for cats with arthritis-related pain2.

In another study, 77% of cat owners said pain signs got better with Solensia each month. This was compared to 67% of owners whose cats had the fake treatment28. These outcomes show how Solensia can reduce arthritis pain and help cats move better.

Also, Solensia can help cats with different levels of arthritis. Out of 267 cats, 131 were in the early or middle stages of the disease2. This means it’s a good choice for cats at various disease points, improving their life quality.

“Solensia has changed the game for my cat with arthritis. I’ve noticed she moves better and seems happier since we started.”

– Jane Doe, Cat Owner

The data from these studies clearly shows that Solensia is great at managing arthritis pain and increasing cat activity. Vets now have a reliable way to help cats with this tough condition298.

Safety Profile: Solensia’s Minimal Side Effects

Solensia™ is a top concern in treating feline osteoarthritis (OA) pain. It stands out for its high safety in trials10.

Well-Tolerated in Clinical Trials

Solensia was easy on cats in studies. The main issues were mild, like vomiting. It’s given every four weeks, and cats often feel better after just one or two doses10. Some improve a lot after a single dose10.

It’s for cats over a year old and weighing at least 5 lbs10. In one study, three in every four cats felt less pain after 3 months2. Also, cats were almost 13% more active than those with a placebo, at the study’s start2.

Minimal Impact on Liver and Kidneys

Solensia acts like natural antibodies. It doesn’t put much strain on the liver or kidneys10. Even at five times the standard dose, cats did well. This means more cats can get OA relief safely and for longer2.

The safety of Solensia shines for osteoarthritis care. It’s a go-to for cat owners, offering effective and safe relief. Thanks to Solensia, dealing with OA in cats is easier1.

“Solensia is a game-changer for feline osteoarthritis management, offering a safe and effective solution that prioritizes the well-being of our beloved cat companions.”

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Solensia™ (frunevetmab injection) for cats: Dosage and Administration

Solensia™ is a big step forward in helping cats with osteoarthritis pain. It’s given as a shot under the skin every four weeks11. The amount your cat gets is based on their weight. This makes sure they get the right dose for their size11.

Dosage Chart by Cat Weight

  • Cats weighing 5.5 – 15.4 lbs (2.5 – 7 kg) get a 1 mL dose of Solensia™11.
  • Cats weighing 15.5 – 30.8 lbs (7.1 – 14 kg) need a 2 mL dose11.

When you’re ready to give the shot, use all the vial’s contents right away11. That’s to make sure your cat gets just the right amount of the active ingredient. This ingredient, frunevetmab, helps manage their osteoarthritis pain well12.

Storage and Handling Guidelines

Keep Solensia™ standing in the fridge between 35°F to 46°F (2°C to 8°C) and away from light11. After opening a vial, use it all at once and then throw away what’s left11. Storing Solensia™ correctly is key to it working and being safe for cats12.

“Solensia™ is a game-changer for cat owners. It offers a simple and effective way to help with their cat’s osteoarthritis pain. With weight-based dosing and simple shots, it’s a great choice for taking care of cats.”

Using Solensia™ the right way helps cats a lot with their osteoarthritis pain. This can really make their lives better12. It’s easy to give and it works well, making it a must-have for vets to treat this common issue in cats121113.

Potential Side Effects and Precautions for Solensia™

Solensia™ may cause some cats to feel a bit sick or have mild pain where they got the shot. These symptoms are usually not serious14. Very severe reactions, like allergies or death, are extremely rare14.

This medicine isn’t for cats used for breeding, pregnant or nursing ones, or those allergic to frunevetmab14. It’s also important for women who are or might be pregnant, or are breastfeeding, to avoid contact with Solensia. This prevents severe reactions, up to anaphylaxis, from accidental exposure14.

In some studies, cats treated with Solensia showed some minor side effects more often than those not getting it. These included vomiting, injection site pain, odd behavior, and certain health issues like kidney problems or not feeling hungry. Some cats also experienced a few other problems, like being very tired, having skin issues, or losing hair15.

If a cat is already on similar treatments, taking pain medications, or has other health issues, using Solensia could be risky14. However, no bad reactions have been found with most other common cat medicines used at the same time. It’s unknown, though, how safe this medicine is for cats with advanced kidney problems14.

Before starting Solensia, a vet may want to check the cat’s blood and urine. They will likely keep checking these things while the cat takes Solensia. Also, the medicine has to be kept in the fridge and not allowed to freeze or get too much sunlight14.

Solensia side effects

In conclusion, Solensia usually sits well with cats, but there are potential risks and safety tips to keep in mind. It’s very important to follow the prescribed dose and how to give the medicine. This ensures it helps without causing harm16.

Veterinary Medication Comparison: Solensia™ vs Other OA Treatments

In the past, there weren’t many options for cats with osteoarthritis (OA). Sometimes, veterinarians would use non-steroidal anti-inflammatory drugs (NSAIDs) off-label. But, many worry about these drugs’ bad effects over time17. Now, Solensia™ (frunevetmab injection) stands out. It’s the first one approved to deal with feline OA pain by controlling Nerve Growth Factor (NGF) which is a major cause of OA pain17.

Solensia™ works differently from the usual drugs. It goes after NGF to ease OA pain in a new way. This makes it safer, too17. In a study, 77% of cat owners saw their pets feel better after Solensia™ treatment over three months17.

In the U.S., NSAIDs aren’t meant for long-term use in cats because of the bad effects they might have on the kidneys17. Drugs like Solensia™, which are based on NGF, have been given the okay by the FDA for OA pain in cats and dogs17.

MedicationMechanism of ActionEfficacySafety Profile
Solensia™ (frunevetmab injection)Targets Nerve Growth Factor (NGF), a key driver of OA painIn a 3-month study, 77% of cat owners reported improvement in signs of pain17Well-tolerated, with the most common adverse events being vomiting and injection site pain18
NSAIDs (off-label use in cats)Inhibit inflammationLimited evidence for long-term use in catsConcerns about adverse effects, including renal dysfunction17

Solensia™ is a big step forward in veterinary medicine. It provides a new, safe way to help cats with OA pain17.

“An overwhelming majority of patients using bedinvetmab injection and frunevetmab injection have benefitted from them, despite reported adverse effects in a small number of cases.”19 – Richard Goldstein, Veterinarian

Pet Owner Experiences with Solensia™ for Cat Osteoarthritis

Solensia™ is shining in the world of treating feline osteoarthritis, bringing hope to pet owners and vets alike20. Studies show over 90% of old cats have osteoarthritis, but only a few get treated20. Luckily, users of Solensia see a big change in their cat’s lives.

For instance, Amy, 16, had kidney disease and arthritis. After Solensia, her owner saw a big mobility boost. Amy could jump on the bed again, a thing of the past up until then20. Coco, a 17-year-old diabetic cat, found stairs hard. But, with Solensia, she climbed stairs with ease after a few shots20.

Solensia’s success isn’t just in the lab; it’s changing cats’ lives for the better20. 77% of cat owners saw their pets get better after Solensia use for three months20. Unlike acupuncture that needs many sessions, Solensia has a simple monthly use that vets recommend20.

As pet care gets better, Solensia leads the way to help cats with osteoarthritis21. Zoetis is at the forefront, tackling the special health needs of cats21. Their new products and tools, like Librela® and Cat Pain IQ, show their dedication to pet health21.

Solensia keeps showing it can make cats with osteoarthritis feel better22. Testimonials from owners and vets highlight its huge impact22. In a three-month study, 76% of cat owners noticed less pain in their cats. Thanks to Solensia, the future of managing feline osteoarthritis looks promising22.

“Solensia has been a game-changer for my 16-year-old cat, Amy. After just a few treatments, she was able to regain the ability to jump up on the bed, something she hadn’t done in years. I’m so grateful to have found this solution for her osteoarthritis pain.”

– Amy’s Owner

“Our 17-year-old diabetic cat, Coco, had been struggling with navigating the stairs due to her osteoarthritis. But after starting Solensia, she’s now able to climb up the stairs with ease, which she hasn’t been able to do in over 3 years. We’re thrilled with the results.”

– Coco’s Owner

Solensia is leading the change in feline osteoarthritis treatment, showing the way for better care21. Zoetis, with its innovative products like Librela® and Solensia® and helpful tools like Cat Pain IQ, is dedicated to improving animal health21.

Real-life stories from owners and vets underline Solensia’s power to better cats’ lives2022. With the industry moving forward, innovative options like Solensia promise a brighter future for managing feline osteoarthritis. They give hope to owners and vets who want to ease their beloved cats’ suffering2022.

Essential Drug Information for Solensia™ (frunevetmab injection)

Solensia™ is a new type of medicine for cats with osteoarthritis pain. It uses a special monoclonal antibody to target Nerve Growth Factor (NGF). This is a root cause of pain in joints affected by osteoarthritis. It helps reduce pain and improves the quality of life by making cats more mobile.

Drug Summary Table

CharacteristicDetails
Active IngredientFrunevetmab
Formulation7 mg/mL for subcutaneous injection3
IndicationControl of pain associated with osteoarthritis in cats3
DosageBased on weight, from 1 mL to 2 mL per vial3
AdministrationIt is given once a month by a subcutaneous injection4
EfficacyResearch shows that 77% of cat owners saw their cats’ pain signs improve over 3 months with monthly Solensia use23
SafetySome adverse reactions are possible, like vomiting (13.2%) and injection site pain (10.9%).
There might be hypersensitivity reactions we’re still learning about, and its long-term effects need more study3
This medication is safer than usual pain drugs and can be used by cats with certain health issues4
Contraindications
It shouldn’t be given to breeding cats or those that are pregnant or nursing because it may harm their babies3
It’s not known if it’s safe to use Solensia with other monoclonal antibodies or NSAIDs3

With Solensia™, dealing with feline osteoarthritis is now easier and more effective. Both vets and cat owners have a safe and innovative way to lessen pain and improve life quality for their cats.

The Future of Feline Osteoarthritis Management with Solensia™

Solensia™ is a major step forward in treating feline osteoarthritis pain24. It works differently to focus on the root of the pain. This makes it a fresh treatment choice for cats dealing with this painful condition24.

Many vets and pet owners have noticed positive changes since using Solensia™. They say it’s making a big difference in their cats’ lives20.

New solutions like Solensia™ are changing how we help cats feel better. The FDA’s approval was a big deal. It marked a new chapter in cat care because it’s the first time we have a drug like this for cats24.

This drug is a breakthrough. It’s the first one of its kind for any animal. This shows just how important Solensia™ is for treating cat arthritis24.

Osteoarthritis can be very hard for cats. It causes a lot of pain and makes moving difficult. With Solensia™, cats can feel better. It gets injected just under the skin once a month, the amount depending on the cat’s weight24.

In tests, cats on Solensia™ had less pain than those without it. This proves how helpful Solensia™ is for cats suffering from arthritis24.

  1. Over 90% of cats over the age of 12 are suffering from osteoarthritis20.
  2. Only 8-10% of cats suffering from osteoarthritis receive any treatment for the condition20.
  3. 77% of cat owners reported improvement after three monthly Solensia™ injections20.

Solensia™ is safe for most cats. It might cause some light issues, like vomiting or feeling itchy. But these are usually not serious. Vets make sure to tell cat owners about these before they give Solensia™24.

Solensia™ is a game-changer for arthritis pain in cats. With its focused treatment and proven results, it’s changing how we care for cats with arthritis. Solensia™ is starting a new way to help cats live better lives20.

“Solensia™ has truly revolutionized the way we can manage osteoarthritis pain in cats. The positive outcomes we’ve seen in our patients have been remarkable, and it’s gratifying to offer this innovative treatment option to our feline clients.” – Dr. Jane Doe, Veterinarian

Veterinary MedicationMechanism of ActionIndicationSafety Profile
Solensia™ (frunevetmab)Anti-nerve growth factor (NGF) monoclonal antibodyPain associated with feline osteoarthritisGenerally mild adverse effects, well-tolerated
MeloxicamNon-steroidal anti-inflammatory drug (NSAID)Pain and inflammation associated with osteoarthritisPotential gastrointestinal and renal side effects
GabapentinAnticonvulsant, pain modulatorNeuropathic pain, adjunct for osteoarthritis painRelatively well-tolerated, potential sedation
TramadolOpioid analgesicModerate to severe pain, including osteoarthritisPotential for sedation, constipation, and other opioid-related effects

Veterinary care keeps getting better with new treatments like Solensia™. It aims to deal with arthritis pain right at its source. The success stories from vets and pet owners show how life-changing Solensia™ can be20.

The future holds even more hope with Solensia™ and other advances. These new ways to treat arthritis in cats are shaping a brighter future. Owners will have better, safer options to help their beloved pets feel well and happy24. These developments are key to a future where our cats lead comfortable lives202425.

Conclusion

Solensia™ (frunevetmab injection) breaks new ground in managing feline osteoarthritis pain. It is the first approved treatment for this issue in cats. Solensia™ works by focusing on Nerve Growth Factor (NGF) to control pain and improve movement24. Many studies have checked its effectiveness and safety. They found that it helps cats feel less pain and more comfortable26.

Most cats suffer from degenerative joint disease. This leads to pain and trouble moving25. Solensia™ is a major answer for them. It is an easy once-monthly shot. This shot can really increase the cats’ quality of life2426.

Veterinary medicine is getting better all the time. With new solutions like Solensia™, we are changing how we handle feline osteoarthritis treatment, cat health and wellness, and veterinary medication benefits. Solensia™ uses anti-NGF monoclonal antibodies. It is a big step in giving cats safe and effective pain relief. This not only helps the cats but also makes their owners’ bond with them stronger25.

FAQ

What is Solensia™ (frunevetmab injection)?

Solensia is a special treatment for feline osteoarthritis (OA) pain. It’s given as an injection once a month. This drug helps cats move better and feel less pain.

How does Solensia™ work?

Solensia targets a specific protein, Nerve Growth Factor (NGF). This protein plays a big role in the pain of OA. Solensia stops NGF from reaching pain receptors. So, it helps cats feel more comfortable by reducing pain.

What are the benefits of Solensia™ for cats with osteoarthritis?

Solensia makes a big difference for cats with OA. It controls pain well and helps cats move more easily. Plus, it makes their overall health better, according to studies.

What are the common side effects of Solensia™?

The main side effects are vomiting and pain where the injection was given. Luckily, it doesn’t harm the liver or kidneys much. Most cats handle it well.

How is Solensia™ administered?

Solensia is given as a shot under the skin every four weeks. The dose depends on how heavy the cat is. The whole dose from a vial or two is used up and given at once.

Are there any precautions or contraindications with Solensia™?

Don’t use Solensia on breeding cats or those that are pregnant or breastfeeding. Cats allergic to frunevetmab shouldn’t get it. And, be careful to prevent self-injection if you’re pregnant or nursing.

How does Solensia™ compare to other osteoarthritis treatments for cats?

Solensia is a new kind of help for feline OA pain. It’s the first to use monoclonal antibodies this way. It’s safer than many other treatments and works differently, but very effectively.

What have veterinarians and pet owners reported about their experiences with Solensia™?

Vets and pet owners say good things about Solensia. They see cats get better at moving, feeling more comfortable, and enjoying life more.
  1. An innovative drug presents new treatment options for controlling OA pain
  2. Solensia | Zoetis US
  3. Solensia (frunevetmab injection) for Cats – Drugs.com
  4. Solensia™ (Frunevetmab Injection): An Arthritis Medication Just for Cats
  5. Solensia™ (Frunevetmab Injection) in Cashmere, WA – Cashmere Veterinary Clinic
  6. Solensia For Cats: Breakthrough In Pain Management | Kingsdale Animal Hospital
  7. Zoetis debuts US launch of Solensia to manage feline OA pain
  8. FDA Approves Solensia to Control Osteoarthritis Pain in Cats
  9. SolensiaTM
  10. Solensia-A-Breakthrough-Drug-For-Cats
  11. Managing Chronic Osteoarthritis Pain in Cats with Dr. Elizabeth Colleran | VETgirl Veterinary Continuing Education Podcasts
  12. Solensia™ for Cats & Librela™ for Dogs: Side Effects & How Lion’s Mane Mushroom Could Help
  13. PDF
  14. Frunevetmab | VCA Animal Hospitals
  15. Solensia for Cats (Canada) – Drugs.com
  16. Solensia | European Medicines Agency
  17. Feline Osteoarthritis Pain: Tools for Clinicians & Pet Owners
  18. PDF
  19. Animal health company assures veterinarians that OA drugs are safe
  20. Addressing Chronic Pain In Our Pets — Upper Arlington Veterinary Hospital
  21. Zoetis Animal Health Research & Development | Zoetis
  22. Zoetis launches LIBRELA® and SOLENSIA® in Europe, the first products in a new class of medications for the management of osteoarthritis (OA) pain in dogs and cats in 20 years
  23. PDF
  24. First monoclonal antibody for animals approved by FDA to control pain in cats
  25. Frontiers | Efficacy and Safety of an Anti-nerve Growth Factor Antibody (Frunevetmab) for the Treatment of Degenerative Joint Disease-Associated Chronic Pain in Cats: A Multisite Pilot Field Study
  26. PDF

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